background strain dba 2j mice control (Jackson Laboratory)
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Background Strain Dba 2j Mice Control, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 86 stars, based on 1 article reviews
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1) Product Images from "Positive allosteric modulator of SERCA pump NDC-1171 attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy"
Article Title: Positive allosteric modulator of SERCA pump NDC-1171 attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy
Journal: bioRxiv
doi: 10.64898/2026.03.05.709950
Figure Legend Snippet: Study design outlining treatment of DBA/2J (control), D2. mdx vehicle, and D2. mdx NDC□1171 groups (n = 9 per group). Mice received oral gavage from 6 to 14 weeks of age. Ultrasound transducer icons denote timepoints at which transthoracic echocardiography wa performed (baseline: 6, midpoint: 11, endpoint: 14, and post-behavior: 16 weeks of age; n□=□5–6 per group). Behavioral testing icon represents the functional behavior testing (treadmill exhaustion and four□limb grip strength) conducted at week 15. Mice were euthanized at week 17 and cardiac tissue was collected for histological evaluation.
Techniques Used: Control, Functional Assay
Figure Legend Snippet: D2. mdx vehicle-treated mice (Vehicle) had impairments when compared to DBA/2J vehicle-treated (Control) in both (A) Four-limb grip strength test and (B) Treadmill exhaustion test. D2. mdx mice treated with NDC-1171 did not improve in either behavior assessments. * p <0.05, ** p <0.01, and *** p <0.001.
Techniques Used: Control